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Salivary Microbiota Is Significantly Less Diverse in Patients with Chronic Spontaneous Urticaria Compared to Healthy Controls: Preliminary Results
Life, 11 (2021), 12; 1329. https://doi.org/10.3390/life11121329
Ćesić, Diana; Lugović-Mihić, Liborija; Ferček, Iva; Gverić Grginić, Ana; Jelić, Marko; Bešlić, Iva; Tambić Andrašević, Arjana

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Ćesić, D., Lugović Mihić, L., Ferček, I., Gverić Grginić, A., Jelić, M., Bešlić, I. i Tambić Andrašević, A. (2021). Salivary Microbiota Is Significantly Less Diverse in Patients with Chronic Spontaneous Urticaria Compared to Healthy Controls: Preliminary Results. Life, 11. (12). doi: 10.3390/life11121329

Ćesić, Diana, et al. "Salivary Microbiota Is Significantly Less Diverse in Patients with Chronic Spontaneous Urticaria Compared to Healthy Controls: Preliminary Results." Life, vol. 11, br. 12, 2021. https://doi.org/10.3390/life11121329

Ćesić, Diana, Liborija Lugović Mihić, Iva Ferček, Ana Gverić Grginić, Marko Jelić, Iva Bešlić i Arjana Tambić Andrašević. "Salivary Microbiota Is Significantly Less Diverse in Patients with Chronic Spontaneous Urticaria Compared to Healthy Controls: Preliminary Results." Life 11, br. 12 (2021). https://doi.org/10.3390/life11121329

Ćesić, D., et al. (2021) 'Salivary Microbiota Is Significantly Less Diverse in Patients with Chronic Spontaneous Urticaria Compared to Healthy Controls: Preliminary Results', Life, 11(12). doi: 10.3390/life11121329

Ćesić D, Lugović Mihić L, Ferček I, Gverić Grginić A, Jelić M, Bešlić I, i sur.. Salivary Microbiota Is Significantly Less Diverse in Patients with Chronic Spontaneous Urticaria Compared to Healthy Controls: Preliminary Results. Life [Internet]. 01.12.2021. [pristupljeno 11.12.2024.];11(12). doi: 10.3390/life11121329

D. Ćesić, et al., "Salivary Microbiota Is Significantly Less Diverse in Patients with Chronic Spontaneous Urticaria Compared to Healthy Controls: Preliminary Results", Life, vol. 11, br. 12, Prosinac 2021. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:127:678246. [Citirano: 11.12.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:127:678246
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Podaci o radu
Naslov (engleski)Salivary Microbiota Is Significantly Less Diverse in Patients with Chronic Spontaneous Urticaria Compared to Healthy Controls: Preliminary Results
AutorDiana Ćesić
AutorLiborija Lugović-Mihić
MBZ: 215056
AutorIva Ferček
AutorAna Gverić Grginić
AutorMarko Jelić
AutorIva Bešlić
AutorArjana Tambić Andrašević
Autorova ustanova(Klinički bolnički centar Sestre milosrdnice)
Autorova ustanovaSveučilište u Zagrebu
Stomatološki fakultet
(Katedra za dermatovenerologiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Dermatovenerologija
Sažetak (engleski)
Background: Because of the important role in regulating the immune system, increasing evidence suggests a possible implication of gut microbiota in Chronic spontaneous urticaria (CSU). Although the oral cavity is the first site of contact between microbiota and the immune system, the association between salivary microbiota and CSU has not yet been reported. Objective: This case-control study aimed to compare differences in salivary microbiota between CSU patients and healthy controls (HC). Twenty-three participants—13 patients with CSU and 10 HC were enrolled; salivary microbiota was determined by molecular approach targeting 16S ribosomal RNA. Terminal restriction fragment length polymorphism (T-RFLP) analysis was performed. Results: Alpha diversity of salivary microbiota in CSU patients was significantly reduced compared to HC, resulting in alteration of the community composition. Species richness determined via the Shannon index was significantly reduced in the CSU group. Conclusion: Dysbiosis of salivary microbiota may contribute to a dysregulated immune system in the development of CSU. To our knowledge, this was the first study that reported an alteration in salivary microbiota composition in CSU patients.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaLife
Brojčani podacivol. 11, br. 12, 1329
e-ISSN2075-1729
DOIhttps://doi.org/10.3390/life11121329
URN:NBNurn:nbn:hr:127:678246
Datum objave publikacije2021-12-01
URL dokumentahttps://www.mdpi.com/2075-1729/11/12/1329
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2022-11-03 12:19:08