DESKVAMATIVNI GINGIVITIS U DIFERENCIJALNOJ DIJAGNOSTICI IMUNOLOŠKIH ORALNIH BOLESTI

professional thesis

• Title (english): Desquamative gingivitis as differential diagnosis of immunological oral diseases
• Author: Nives Romana Beketić Lušić
• Mentor: Ivan Alajbeg (mentor)
• Committee member: Mirna Šitum
• Committee member: Ivan Alajbeg
• Committee member: Vanja Vučićević-Boras
• Granter: University of Zagreb; School of Dental Medicine; (Department of Oral Medicine); Zagreb
• Defense date and country: 2013-02-21, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Dental Medicine; Oral Medicine

Abstract

Deskvamativni gingivitis (DG) je deskriptivni termin koji se koristi za opisivanje epitelne deskvamacije, eritema, erozija i/ili vezikulobuloznih lezija gingive. DG je povezan s nekoliko mukokutanih poremećaja i sistemskih stanja koja imaju lošu prognozu i visoki morbiditet. Međutim, ne postoje jasni podaci u pogledu frekvencije povezanosti ovih bolesti. Oralni lihen planus, pemfigus vulgaris i cikatrizacijski pemfigoid odgovorni su za većinu slučajeva DG-a. Moraju se uzeti u obzir i drugi poremećaji poput: eksudativni multiformni eritem, eritematozni lupus, bolest presatka protiv primatelja, kronični ulcerativni stomatitis, linearna IgA bolest, herpetiformni dermatitis, bulozna epidermoliza acquisita, gingivitis izazvan lijekovima i psorijaza. Često su potrebna točna klinička, histološka i imunološka istraživanja da bi se diferenciralo između poremećaja povezanih s DG-om, moglo omogućiti adekvatnu terapiju i poboljšati prognoze pacijenta. Vrlo je važna svjesnost ovog rijetkog kliničkog entiteta kako bismo razlikovali deskvamativni ginivitis od gingivitisa uzrokovanog plakom. Gingivitis uzrokovan plakom je vrlo uobičajeno stanje, koje lako prepoznaju i svakodnevno tretiraju doktori dentalne medicine. Rano prepoznavanje ovih lezija može spriječiti zakašnjelu dijagnozu i neprikladnu terapiju potencijalno ozbiljnih oralnih i dermatoloških bolesti.

Abstract (english)

Desquamative gingivitis (DG) is a descriptive term used to indicate epithelial desquamation, erythema, erosions, and/or vesiculobullous lesions of the gingiva. DG is commonly associated with several mucocutaneous disorders and systemic conditions that may carry a poor prognosis and high morbidity. However, there are no clear data concerning the frequency of these disease associations. Oral lichen planus, pemphigus vulgaris and mucous membrane pemphigoid are responsible for the majority of cases of DG. In addition, other uncommon disorders should be considered, such as erythema exudativum multiforme, lupus erythematosus, graft versus host disease, chronic ulcerative stomatitis, linear immunoglobulin (Ig) A disease, dermatitis herpetiformis, epidermolysis bullosa acquisita, drug induced DG and psoriasis. Accurate clinical, histological and immunological investigations are often required to differentiate among DG-associated disorders, provide adequate therapy and improve the prognosis of patients. It is important to be aware of this rare clinical entity so as to distinguish DG from plaque induced gingivitis. Plaque induced gingivitis is an extremly common condition, easily recognized and treated by the dental practitioner. An early recognition of these lesions may prevent delayed diagnosis and inappropriate treatment of potentially serious dermatological diseases.

• Keywords: gingivitis
• Keywords (english): gingivitis
• Language: croatian
• URN:NBN: urn:nbn:hr:127:009386
• Study programme: Title: dental medicine; Study programme type: university; Study level: postgraduate specialist; Academic / professional title: sveučilišni/a magistar/magistra dentalne medicine (sveučilišni/a magistar/magistra dentalne medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2016-03-22 10:56:03