Effect of L-arginine dietary supplementation on salivary urea concentration and pH in physically active individuals

Znanstveni rad - Izvorni znanstveni rad

• Autor: L Vuletic
• Autor: S Spalj
• Autor: D Rogic
• Autor: L Ruzic
• Autor: I Alajbeg
• Autorova ustanova: (Klinički bolnički centar Zagreb)
• Autorova ustanova: Sveučilište u Rijeci; (Fakultet dentalne medicine)
• Autorova ustanova: Sveučilište u Zagrebu; Farmaceutsko-biokemijski fakultet
• Autorova ustanova: Sveučilište u Zagrebu; Stomatološki fakultet
• Znanstveno / umjetničko područje, polje i grana: BIOMEDICINA I ZDRAVSTVO; Dentalna medicina

Sažetak (engleski)

Background The aim of this study was to assess if the consumption of 3 g of a commercially available L-arginine dietary supplement causes a postabsorptive rise in urea concentration or pH of unstimulated saliva in a group of physically active individuals. Methods Salivary urea and pH were determined for 117 participants in a randomized double-blinded placebo-controlled study. Samples were collected by 'spitting' method in fasting conditions. One hour prior to their second visit, participants consumed three tablets of L-arginine or placebo. Results Urea concentration was significantly lower at second measurement for both the study and control group. The magnitude of the change was not significant between the groups. pH was higher for both groups at second measurement, but only significant for the study group. The magnitude of the change was significant between the groups. Participants who intermittently ingested protein dietary supplements and those with a Body Mass Index (BMI) higher than 25 had significantly higher basal urea concentration. Conclusions The results of this study did not confirm the hypothesis. Further studies are needed to determine the effects of different doses of L-arginine supplements on the biochemical composition of saliva and the influence of their long-term consumption on the risk of developing dental diseases.

• Ključne riječi (engleski): L-arginine; oral health promotion; salivary pH; salivary urea; unstimulated saliva
• Jezik: engleski
• Vrsta publikacije: Znanstveni rad - Izvorni znanstveni rad
• Status objave: Objavljen
• Vrsta recenzije: Recenziran - međunarodna recenzija
• Verzija publikacije: Objavljena verzija rada (izdavačev PDF)
• Naslov časopisa: Australian Dental Journal
• Brojčani podaci: vol. 58, br. 4, str. 491-497
• p-ISSN: 0045-0421
• DOI: https://doi.org/10.1111/adj.12114
• URN:NBN: urn:nbn:hr:127:662435
• Datum objave publikacije: 2013-12
• URL dokumenta: https://onlinelibrary.wiley.com/doi/10.1111/adj.12114
• Vrsta resursa: Tekst
• Prava pristupa: Otvoreni pristup
• Datum i vrijeme pohrane: 2024-10-30 11:27:52