prikaz prve stranice dokumenta Association between Salivary Cortisol and α-Amylase with the Psychological Profile of Patients with Oral Lichen Planus and Burning Mouth Syndrome: A Case–Control Study
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Association between Salivary Cortisol and α-Amylase with the Psychological Profile of Patients with Oral Lichen Planus and Burning Mouth Syndrome: A Case–Control Study
Biomedicines, 11 (2023), 8; 2182. https://doi.org/10.3390/biomedicines11082182
Glavina, Ana; Lugović-Mihić, Liborija; Martinović, Dinko; Cigić, Livia; Tandara, Leida; Lukenda, Marino; Biočina-Lukenda, Dolores; Šupe-Domić, Daniela

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Glavina, A., Lugović Mihić, L., Martinović, D., Cigić, L., Tandara, L., Lukenda, M. ... Šupe Domić, D. (2023). Association between Salivary Cortisol and α-Amylase with the Psychological Profile of Patients with Oral Lichen Planus and Burning Mouth Syndrome: A Case–Control Study. Biomedicines, 11. (8). doi: 10.3390/biomedicines11082182

Glavina, Ana, et al. "Association between Salivary Cortisol and α-Amylase with the Psychological Profile of Patients with Oral Lichen Planus and Burning Mouth Syndrome: A Case–Control Study." Biomedicines, vol. 11, br. 8, 2023. https://doi.org/10.3390/biomedicines11082182

Glavina, Ana, Liborija Lugović Mihić, Dinko Martinović, Livia Cigić, Leida Tandara, Marino Lukenda, Dolores Biočina Lukenda i Daniela Šupe Domić. "Association between Salivary Cortisol and α-Amylase with the Psychological Profile of Patients with Oral Lichen Planus and Burning Mouth Syndrome: A Case–Control Study." Biomedicines 11, br. 8 (2023). https://doi.org/10.3390/biomedicines11082182

Glavina, A., et al. (2023) 'Association between Salivary Cortisol and α-Amylase with the Psychological Profile of Patients with Oral Lichen Planus and Burning Mouth Syndrome: A Case–Control Study', Biomedicines, 11(8). doi: 10.3390/biomedicines11082182

Glavina A, Lugović Mihić L, Martinović D, Cigić L, Tandara L, Lukenda M, i sur.. Association between Salivary Cortisol and α-Amylase with the Psychological Profile of Patients with Oral Lichen Planus and Burning Mouth Syndrome: A Case–Control Study. Biomedicines [Internet]. 03.08.2023. [pristupljeno 19.04.2024.];11(8). doi: 10.3390/biomedicines11082182

A. Glavina, et al., "Association between Salivary Cortisol and α-Amylase with the Psychological Profile of Patients with Oral Lichen Planus and Burning Mouth Syndrome: A Case–Control Study", Biomedicines, vol. 11, br. 8, Kolovoz 2023. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:127:976758. [Citirano: 19.04.2024.]

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Podaci o radu
Naslov (engleski)Association between Salivary Cortisol and α-Amylase with the Psychological Profile of Patients with Oral Lichen Planus and Burning Mouth Syndrome: A Case–Control Study
AutorAna Glavina
AutorLiborija Lugović-Mihić
MBZ: 215056
AutorDinko Martinović
AutorLivia Cigić
AutorLeida Tandara
AutorMarino Lukenda
AutorDolores Biočina-Lukenda
AutorDaniela Šupe-Domić
Autorova ustanovaSveučilište u Splitu
Autorova ustanova(Klinički bolnički centar Sestre milosrdnice)
Autorova ustanova(Klinički bolnički centar Split)
Autorova ustanovaSveučilište u Zagrebu
Stomatološki fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Dentalna medicina
Sažetak (engleski)
The aim of our study was to assess the relationship between the concentration/activity of salivary stress biomarkers (cortisol, α-amylase) and the psychological profile of patients with oral lichen planus (OLP) and primary burning mouth syndrome (BMS). A total of 160 subjects participated in this case–control study: 60 patients with OLP; 60 patients with primary BMS; and 40 control subjects. Unstimulated whole saliva (UWS) was collected between 9 and 10 a.m. Salivary biomarkers were analyzed by enzyme-linked immunosorbent assays (ELISAs). Psychological assessment was evaluated with the Depression, Anxiety, and Stress Scale (DASS-21). The patients with primary BMS had higher salivary cortisol concentrations and α-amylase activity (0.52 vs. 0.44 µg/dL; 160,531 vs. 145,804 U/L; one-way analysis of variance (ANOVA) with post hoc Scheffe test) compared with patients with OLP. The patients with primary BMS had statistically significant higher scores for depression, anxiety, and stress compared with patients with OLP and control subjects (p < 0.001, Kruskal–Wallis test). There was a strong positive correlation between anxiety and depression, stress and depression, and stress and anxiety in patients with OLP and BMS (p < 0.001 and p < 0.001, respectively; Spearman’s correlation). There was a good positive correlation between symptom intensity (pain/burning) and psychological profile (depression, anxiety, stress) in patients with primary BMS (r = 0.373, p = 0.003; r = 0.515, p < 0.001; r = 0.365, p = 0.004, respectively; Spearman’s correlation). This case–control study is the first to compare the psychoendocrinological profile of patients with two different oral diseases. The patients with BMS showed a higher concentration/activity of salivary stress biomarkers (cortisol, α-amylase) and a stronger association with mental disorders compared with patients with OLP. However, an interdisciplinary psychoneuroimmunological approach is equally important in both patient groups (OLP and BMS), regardless of whether mental disorders are the cause or the consequence.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaBiomedicines
Brojčani podacivol. 11, br. 8, 2182
e-ISSN2227-9059
DOIhttps://doi.org/10.3390/biomedicines11082182
URN:NBNurn:nbn:hr:127:976758
Datum objave publikacije2023-08-03
URL dokumentahttps://www.mdpi.com/2227-9059/11/8/2182
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2023-10-02 07:59:53