prikaz prve stranice dokumenta Gut Microbiome Composition in Patients with Chronic Urticaria: A Review of Current Evidence and Data
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Gut Microbiome Composition in Patients with Chronic Urticaria: A Review of Current Evidence and Data
Life, 13 (2023), 1; 152. https://doi.org/10.3390/life13010152
Krišto, Mirela; Lugović-Mihić, Liborija; Muñoz, Melba; Rupnik, Maja; Mahnic, Aleksander; Ozretić, Petar; Jaganjac, Morana; Ćesić, Diana; Kuna, Matea

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Krišto, M., Lugović Mihić, L., Muñoz, M., Rupnik, M., Mahnic, A., Ozretić, P. ... Kuna, M. (2023). Gut Microbiome Composition in Patients with Chronic Urticaria: A Review of Current Evidence and Data. Life, 13. (1). doi: 10.3390/life13010152

Krišto, Mirela, et al. "Gut Microbiome Composition in Patients with Chronic Urticaria: A Review of Current Evidence and Data." Life, vol. 13, br. 1, 2023. https://doi.org/10.3390/life13010152

Krišto, Mirela, Liborija Lugović Mihić, Melba Muñoz, Maja Rupnik, Aleksander Mahnic, Petar Ozretić, Morana Jaganjac, Diana Ćesić i Matea Kuna. "Gut Microbiome Composition in Patients with Chronic Urticaria: A Review of Current Evidence and Data." Life 13, br. 1 (2023). https://doi.org/10.3390/life13010152

Krišto, M., et al. (2023) 'Gut Microbiome Composition in Patients with Chronic Urticaria: A Review of Current Evidence and Data', Life, 13(1). doi: 10.3390/life13010152

Krišto M, Lugović Mihić L, Muñoz M, Rupnik M, Mahnic A, Ozretić P, i sur.. Gut Microbiome Composition in Patients with Chronic Urticaria: A Review of Current Evidence and Data. Life [Internet]. 04.01.2023. [pristupljeno 21.04.2024.];13(1). doi: 10.3390/life13010152

M. Krišto, et al., "Gut Microbiome Composition in Patients with Chronic Urticaria: A Review of Current Evidence and Data", Life, vol. 13, br. 1, Siječanj 2023. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:127:859176. [Citirano: 21.04.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:127:859176
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Naslov (engleski)Gut Microbiome Composition in Patients with Chronic Urticaria: A Review of Current Evidence and Data
AutorMirela Krišto
AutorLiborija Lugović-Mihić
MBZ: 215056
AutorMelba Muñoz
AutorMaja Rupnik
AutorAleksander Mahnic
AutorPetar Ozretić
AutorMorana Jaganjac
AutorDiana Ćesić
AutorMatea Kuna
Autorova ustanovaInstitut Ruđer Bošković
Autorova ustanova(Klinički bolnički centar Sestre milosrdnice)
Autorova ustanovaSveučilište u Zagrebu
Stomatološki fakultet
(Katedra za dermatovenerologiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
Recent studies have linked gut microorganism composition and chronic urticaria (CU); however, the underlying mechanisms responsible for this connection are unknown. Since the human immune system is in homeostasis with microbiota, and the composition of the microbiome regulates the development and function of the immune system, it is likely that an alteration of microbiota components (a dysbiosis) could influence the course of chronic spontaneous urticaria (CSU), including disease severity, patient quality of life and treatment outcome. To date, several studies have identified changes in the gut microbiota composition of patients with CSU, though only a few have exhibited metabolic abnormalities associated with gut dysbiosis. The studies on CSU patients predominantly showed that the relative abundance of beneficial bacteria was decreased (Firmicutes and Bacteroides), while that of opportunistic bacteria was increased (Enterobacteria and Proteobacteria). In addition, serum metabolome analysis revealed that gut microbiota-associated alterations in unsaturated fatty acids and the butanoate metabolism pathway may play a role in CSU. These findings are potentially associated with inflammation mediated by the imbalance of Th1/Th2/Th17 cytokines, which might contribute to CSU pathogenesis. Further research in this field could improve clinical, diagnostic, and therapeutic approaches to patients with CSU. By applying new knowledge on gut microbial communities and metabolomics, future CSU therapies could modify the microbiota composition using agents such as probiotics or other similar agents, which, in combination with current standard therapies, could hopefully lead to a reduction in symptoms and an improved quality of life for CSU patients.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaLife
Brojčani podacivol. 13, br. 1, 152
e-ISSN2075-1729
DOIhttps://doi.org/10.3390/life13010152
URN:NBNurn:nbn:hr:127:859176
Datum objave publikacije2023-01-04
URL dokumentahttps://www.mdpi.com/2075-1729/13/1/152
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2023-03-03 08:59:12