Dijagnostika i liječenje tumora epifarinksa

master's thesis

• Title (english): Diagnosis and Treatment of Nasopharyngeal Tumors
• Author: Maja Krpan
• Mentor: Davor Vagić (mentor)
• Committee member: Davor Vagić (predsjednik povjerenstva)
• Committee member: Goran Geber (član povjerenstva)
• Committee member: Robert Trotić (član povjerenstva)
• Granter: University of Zagreb; School of Dental Medicine; (Chair of Otorhynolaringology); Zagreb
• Defense date and country: 2016-09-29, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Dental Medicine

Abstract

Velik broj različitih tumora može proizaći iz nazofarinksa. Juvenilni
angiofibrom je rijedak tumor, ali je najčešća benigna neoplazma nazofarinksa.
JNA je spororastući vaskularni tumor i najčešće pogađa mlađe muškarce između
10. i 25. godine života.
Najčešći simptomi uključuju začepljenost nosa (najčešće unilateralno), iscjedak
iz nosa i gubitak sluha.
Liječi se kirurški endoskopskim putem.
NPC je najčešći zloćudni tumor u epifarinksu. Uzrokovan je kombinacijom
različitih faktora: virusnih, okolišnih i nasljednih.
Virusni utjecaj je povezan s infekcijom Epstein-Barrovim virusom (EBV).
Liječenje uključuje radioterapiju, kemoterapiju ili kombinaciju i jednog i drugog.
NPC se očituje presadnicama (metastazama) u limfnim čvorovima u više od
polovice oboljelih.
Kirurški mu se pristupa ako je bolesniku potrebno spasiti život.
Često se izvodi postupak radikalne disekcije vrata.

Abstract (english)

A large number of different tumors can arise in the nasopharynx.
Juvenile angiofibroma of the nasopharynx is rare but is the most common benign
neoplasm of the nasopharynx. JNA is a slow-growing vascular tumor and usually
occurs in adolescent males, between the ages of 10 and 25.
The most common symptoms include nasal obstruction (usually unilateral), nasal
discharge and conductive hearing loss.
In most cases JNA is treated surgically and the endoscopic route is being used
more frequently.
NPC is the most common malignancy in the nasopharynx. It is caused by
combination of factors: viral, environmental influences, and heredity. The viral
influence is associated with Epstein-Barr virus (EBV) infection.
The treatment for NPC usually involves radiation therapy, chemotherapy or a
combination of the two.
NPC presents itself with nodal metastasis in more than half of cases.
A surgery is reserved for extreme cases in order to save patient’s life.
A radical neck dissection is the preferred mode of treatment.

• Keywords: ždrijelo; novotvorine
• Keywords (english): nasopharyngeal neoplasms
• Language: croatian
• URN:NBN: urn:nbn:hr:127:494367
• Study programme: Title: dental medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica dentalne medicine (doktor/doktorica dentalne medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2016-11-21 14:11:53