Oralne manifestacije upalnih bolesti crijeva

master's thesis

• Title (english): Oral manifestations of the inflammatory bowel disease
• Author: Ivana Lekšić
• Mentor: Vlaho Brailo (mentor)
• Committee member: Vlaho Brailo (predsjednik povjerenstva)
• Committee member: Ivan Alajbeg (član povjerenstva)
• Committee member: Darko Božić (član povjerenstva)
• Granter: University of Zagreb; School of Dental Medicine; (Department of Oral Medicine); Zagreb
• Defense date and country: 2016-09-09, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Dental Medicine; Oral Medicine

Abstract

Crohnova bolest i ulcerozni kolitis su oblici upalnih bolesti crijeva. Crohnova
bolest javlja se duž cijele dužine probavne cijevi, a zahvaća cijelu debljinu stijenke.
Upalne promjene su diskontinuirane, izmjenjuje se zdrava i bolesna sluznica.
Ulcerozni kolitis je ograničen na sluznicu debelog crijeva. Za razliku od Crohnove
bolesti, upalne promjene su kontinuirane. Oba stanja karakterizirana su kroničnom
upalom gatrointestinalne sluznice, uz koju se u nekim slučajevima javljaju i
izvancrijevne manifestacije.
Oralne manifestacije Crohnove bolesti su: orofacijalni edemi, krpičaste
promjene sluznice, kaldrmast izgled sluznice, hiperplastični gingivitis i aftozni
stomatitis. Najčešće se javljaju na bukalnoj sluznici, gingivi, usnama, vestibulumu i
retromolarnom području. Orofacijalna granulomatoza je neuobičajeno kliničko
patološko stanje koje opisuje pacijente s oralnim manifestacijama identičnima onima
kod Crohnove bolesti, no bolest crijeva nije prisutna. Oralne manifestacije ulceroznog
kolitisa nisu tako upečatljive kao oralne manifestacije Crohnove bolesti. Najčešće se
viđaju aftozni stomatitis i pyostomatitis vegetans.
Terapija oralnih manifestacija usmjerena je liječenju osnovne bolesti. Bolesnici
s upalnom bolesti crijeva liječe se kortikosteroidima i imunosupresivima te je potreban
oprez kod stomatološkog liječenja.

Abstract (english)

Crohn's disease and ulcerative colitis are forms of inflammatory bowel disease.
Crohn's disease is present along the entire length of the gastrointestinal tract, and
involves the entire thickness of the intestinal wall. Inflammatory changes are
discontinuous, with alternating areas of healthy and diseased mucosa. Ulcerative
colitis is confined to the mucosa of the colon. Inflammatory changes, as opposed to
Crohn's disease, are continuous. Both conditions are characterised by the chronic
inflammation of gatrointestinal mucosa, and in some cases extraintestinal
manifestations. Oral manifestations of Crohn's disease are: orofacial oedemas,
mucosal tags, cobblestoning, hyperplastic gingivitis and aphthous stomatitis. They
occur mostly on buccal mucosa, gingiva, lips, vestibule and retromolar area. Orofacial
granulomatosis is an uncommon condition amongst patients with oral lesions identical
to those of Crohn's disease, yet the intestine is unaffected. Oral manifestations of
ulcerative colitis are not as prominent as oral manifestations of Crohn's disease. Most
common features are aphthous stomatitis and pyostomatitis vegetans. Treatment of
oral lesions focuses on the treatment of the underlying disease. Patients with
inflammatory bowel disease are treated with corticosteroids and immune suppressants.
Caution is therefore required during dental treatment.

• Keywords: oralne manifestacije; bolesti crijeva; upalne
• Keywords (english): oral manifestations; inflammatory bowel diseases
• Language: croatian
• URN:NBN: urn:nbn:hr:127:137997
• Study programme: Title: dental medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica dentalne medicine (doktor/doktorica dentalne medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2016-11-11 12:25:15