Predoziranje lijekovima u ordinaciji dentalne medicine

master's thesis

• Title (english): Drug Overdose in the Dental Office
• Author: Eva Krizmanić
• Mentor: Danica Vidović Juras (mentor)
• Committee member: Danica Vidović Juras (predsjednik povjerenstva)
• Committee member: Božana Lončar Brzak (član povjerenstva)
• Committee member: Ana Andabak Rogulj (član povjerenstva)
• Granter: University of Zagreb; School of Dental Medicine; (Department of Oral Medicine); Zagreb
• Defense date and country: 2021-09-21, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Dental Medicine; Oral Medicine

Abstract

Stomatolozi rukuju lijekovima koji mogu uzrokovati predoziranje. Riječ je o lokalnim anesteticima, vazokonstriktorima, sedativima i opioidnim analgeticima. Klinička slika predoziranja nastaje kad količina lijeka u krvi ciljnih organa i tkiva postane viša od terapijske doze. Ona traje sve dok je količina lijeka u krvi iznad praga nastanka reakcije predoziranja. Predoziranje lijekovima u ordinaciji dentalne medicine stanje je na koje stomatolog treba biti spreman brzo reagirati. Na nastanak predoziranja utječu čimbenici vezani uz lijek i čimbenici vezani uz stanje samog pacijenta. Kako bi se izbjeglo, terapeut koristi minimalnu potrebnu
količinu lijeka kojom se postiže terapijski učinak. Detaljnim proučavanjem pacijentove anamneze, kliničkim pregledom te ispravnom uporabom lijeka, učestalost neželjenih reakcija na lijek, poput predoziranja, može se znatno smanjiti. Ukoliko do predoziranja ipak dođe, stomatolog slijedi protokol djelovanja u slučaju predoziranja određenim lijekom i daje pacijentu potrebnu terapiju. Sam odlučuje na temelju vlastitih sposobnosti, težini kliničke slike i opremljenosti dentalne ordinacije lijekovima za određeno predoziranje, hoće li pozvati hitnu pomoć ili ne. Uporaba ranije navedenih lijekova neizbježna je u svakodnevnom radu doktora dentalne medicine, kao i mogućnost nastanka predoziranja ili toksične reakcije. Stoga, on mora biti savjestan pri rukovanju takvim lijekovima i brzo prepoznati simptome predoziranja te kako reagirati.

Abstract (english)

Dentists handle drugs which can cause an overdose. Such are local anesthetics, vasoconstrictors, sedatives, and opioid analgesics. If the amount of a drug in aimed organs and tissues surpasses the therapeutic one, the clinical manifestations of an overdose begin. The clinical manifestation lasts for as long the blood level of the drug – is above the overdose
threshold. Drug overdose in a dental office is an event where the dentist has to be ready to react quickly. The occurrence of an overdose reaction is affected by drug-related factors and the patient’s condition. To avoid it, the therapist uses the minimal quantity of the drug that provides a therapeutic effect. The incidence of an overdose reaction can be significantly decreased by analyzing the patient's medical history, doing a detailed clinical examination, and using the correct quantity of the drug. If an overdose reaction still occurs, the dentist follows a protocol of reaction to treat a specific kind of a drug overdose and provides the necessary therapy. The dentist decides if an ambulance should be called, based on his own aptitude, severity of the clinical manifestations and the equipment available in the dental office. Usage of the earlier mentioned drugs is inevitable in the everyday work of a dentist, as is the possibility of an onset of an overdose or a toxic reaction, which is why a dentist should
conscientiously handle such drugs and be able to quickly recognize the symptoms of an overdose and how to react to them.

• Keywords: oralna medicina; predoziranje lijekovima; nuspojave povezane s lijekovima
• Keywords (english): Oral Medicine; Drug Overdose; Drug-Related Side Effects and Advesre Reaction
• Language: croatian
• URN:NBN: urn:nbn:hr:127:754422
• Study programme: Title: dental medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica dentalne medicine (doktor/doktorica dentalne medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Access restricted to students and staff of home institution
• Created on: 2021-09-29 09:04:02