Impact of rehabilitation versus edentulism on systemic health and quality of life in patients affected by periodontitis: A systematic review and meta‐analysis

Scientific paper - Original scientific paper

• Author: Stefano Gennai
• Author: Rossana Izzetti
• Author: Maria C. Pioli
• Author: Larisa Music
• Author: Filippo Graziani
• Author's institution: University of Zagreb; School of Dental Medicine
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Dental Medicine

Abstract (english)

Aim: To investigate the effect of rehabilitation in fully/partially edentulous patients with stage IV periodontitis on oral-health-related quality of life (OHRQoL) and systemic health. Materials and methods: A systematic electronic and manual search was conducted. Three authors independently reviewed, selected, and extracted the data. Outcomes were OHRQoL (Oral Health Impact Profile 14 [OHIP-14] and OHIP-49, General Oral Health Assessment Index [GOHAI], visual analogue scale, symptoms registration) and systemic health-related outcomes (incidence and prevalence of systemic diseases, values of systemic disease indicators). Qualitative data were synthesized for OHRQoL and systemic health-related outcomes. Meta-analysis was conducted on available quantitative data. Results: The search identified 59 articles (6724 subjects in total). OHRQoL improved across all the studies, irrespective of the number of missing teeth, their location, or treatment modality. Meta-analysis showed significant improvement of OHIP-49 (36.86, p <.01) in manuscripts including subjects affected by periodontitis, consistently with the remaining literature (reduction of score points post rehabilitation: OHIP-14 = 10.52, OHIP-49 = 56.02, GOHAI = 5.40, p <.01 for all). Non-rehabilitated subjects exhibited inferior cognitive status, higher medication intake, and frailty. However, our data are limited and should be interpreted with caution. Conclusions: Oral rehabilitation improves OHRQoL and, potentially, systemic health in edentulous patients. It is unclear whether these findings may be extrapolated to patients with stage IV periodontitis.

• Keywords (english): edentulism; periodontitis stage IV; quality of life; systemic health
• Language: english
• Publication type: Scientific paper - Original scientific paper
• Publication status: Published
• Peer review: Peer review - international
• Publication version: Published version
• Journal title: Journal of Clinical Periodontology
• Numbering: vol. 49, no. S24, pp. 328-358
• p-ISSN: 0303-6979
• e-ISSN: 1600-051X
• DOI: https://doi.org/10.1111/jcpe.13526
• URN:NBN: urn:nbn:hr:127:278154
• Publication: 2021-11-10
• Document URL: https://onlinelibrary.wiley.com/doi/10.1111/jcpe.13526
• Type of resource: Text
• Access conditions: Open access
• Created on: 2024-10-22 07:16:52