Unicistični ameloblastom - tehnike liječenja

master's thesis

• Title (english): Unicystic ameloblastoma – treatment techniques
• Author: Gabrijela Srbljinović
• Mentor: Marko Vuletić (mentor)
• Committee member: Marko Vuletić (predsjednik povjerenstva)
• Committee member: Valentina Rajić (član povjerenstva)
• Committee member: Tomislav Katanec (član povjerenstva)
• Granter: University of Zagreb; School of Dental Medicine; (Department of Oral Surgery); Zagreb
• Defense date and country: 2024-07-12, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Dental Medicine; Oral Surgery

Abstract

Ameloblastom je benigni, ali lokalno invazivni, odontogeni tumor epitelnog porijekla. Najčešće se javlja u mandibuli (80 %) i rjeđe u maksili (20 %). Prema klasifikaciji Svjetske zdravstvene organizacije (WHO) iz 2022. godine ameloblastom se dijeli na konvencionalni, ekstraosealni/periferni, unicistični, metastazirajući i adenoidni ameloblastom. Dijagnostika ameloblastoma uključuje klinički pregled, radiološke metode poput ortopantomograma, CBCT-a i magnetske rezonancije te histopatološku analizu biopsije. Radiološke metode omogućuju vizualizaciju veličine, oblika i lokalizacije tumora, dok histopatologija potvrđuje dijagnozu i određuje tip tumora. Metode liječenja ameloblastoma ovise o veličini, lokalizaciji i tipu tumora. Najčešće korištene metode uključuju dekompresiju, enukleaciju s kiretažom, marginalnu resekciju i segmentalnu resekciju. Dekompresijom se smanjuje veličina tumora te se tako olakšava kasnija kirurška intervencija. Enukleacija s kiretažom omogućava uklanjanje tumora uz minimalno oštećenje okolnog tkiva i smanjenje rizika od recidiva. Marginalna resekcija uklanja tumor zajedno s dijelom zdrave kosti, dok segmentalna resekcija uklanja veći dio zahvaćene čeljusti, često uz potrebu za rekonstrukcijom. Rana dijagnoza ameloblastoma i odgovarajuće planiranje liječenja igraju ključnu ulogu u smanjenju stope postoperativnih komplikacija i recidiva.

Abstract (english)

Ameloblastoma is a benign but locally invasive odontogenic tumor of epithelial origin. It occurs most often in the mandible (80%) and less often in the maxilla (20%). According to the World Health Organization (WHO) in 2022, ameloblastoma is divided into conventional, extraosseous/peripheral, unicystic, metastasizing and adenoid ameloblastoma. Diagnostics of ameloblastoma includes clinical examination, radiological methods such as orthopantomogram, CBCT and magnetic resonance and histopathological biopsy analysis. Radiological methods allow visualization of the size, shape and localization of the tumor, while histopathology confirms the diagnosis and determines the tumor type. Treatment methods for ameloblastoma depend on the size, location and type of tumor. The most commonly used methods include decompression, enucleation with curettage, marginal resection and segmental resection. Decompression reduces the size of the tumor and thus facilitates later surgical intervention. Enucleation with curettage enables the removal of the tumor with minimal damage to the surrounding tissue and also reduces the risk of recurrence. Marginal resection removes the tumor along with part of the healthy bone, while segmental resection removes most of the affected jaw, often with the need for reconstruction. Early diagnosis of ameloblastoma and appropriate treatment planning play a key role in reducing the rate of postoperative complications and recurrence.

• Keywords: ameloblastom; dekompresija; enukleacija; kiretaža
• Keywords (english): ameloblastoma; decompression; enucleation; curettage
• Language: croatian
• URN:NBN: urn:nbn:hr:127:520682
• Study programme: Title: Dental medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica dentalne medicine (doktor/doktorica dentalne medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2024-07-06 19:24:25