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Professional paper - Chapter in Book
Application of Photodynamic Therapy in the Treatment of Osteonecrosis of the Jaw
In: Photodynamic Therapy - from Basic Science to Clinical Research / Inada, Natalia (Ed.). London : Delhi: IntechOpen, 2020. pp. 1-25. https://doi.org/10.5772/intechopen.94257
Vuletić, Marko; Brzak Lončar, Božana; Smojver, Igor; Marković, Luka; Sušić, Mato; Gabrić, Dragana

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Vuletić, M., Brzak Lončar, B., Smojver, I., Marković, L., Sušić, M. & Gabrić, D. (2020). Application of Photodynamic Therapy in the Treatment of Osteonecrosis of the Jaw. In N. Inada, (Ed.), Photodynamic Therapy - from Basic Science to Clinical Research (pp. 1-25). London : Delhi: IntechOpen. doi: 10.5772/intechopen.94257

Vuletić, Marko, et al. "Application of Photodynamic Therapy in the Treatment of Osteonecrosis of the Jaw." Photodynamic Therapy - from Basic Science to Clinical Research, edited by Natalia Inada, IntechOpen, 2020, pp. 1-25. https://urn.nsk.hr/urn:nbn:hr:127:712112

Vuletić, Marko, Božana Brzak Lončar, Igor Smojver, Luka Marković, Mato Sušić and Dragana Gabrić. "Application of Photodynamic Therapy in the Treatment of Osteonecrosis of the Jaw." In Photodynamic Therapy - from Basic Science to Clinical Research, edited by Natalia Inada, 1-25. London : Delhi: IntechOpen, 2020. https://urn.nsk.hr/urn:nbn:hr:127:712112

Vuletić, M., et al. (2020) 'Application of Photodynamic Therapy in the Treatment of Osteonecrosis of the Jaw' in Inada, N. (ed.) Photodynamic Therapy - from Basic Science to Clinical Research London : Delhi: IntechOpen, pp. 1-25. Available at: https://urn.nsk.hr/urn:nbn:hr:127:712112 (Accessed 09 May 2024)

Vuletić M, Brzak Lončar B, Smojver I, Marković L, Sušić M, Gabrić D. Application of Photodynamic Therapy in the Treatment of Osteonecrosis of the Jaw. In: N. Inada, ed. Photodynamic Therapy - from Basic Science to Clinical Research. London : Delhi: IntechOpen; 2020. Pp. 1-25. [cited 2024 May 09] Available at: https://urn.nsk.hr/urn:nbn:hr:127:712112

M. Vuletić, B. Brzak Lončar, I. Smojver, L. Marković, M. Sušić and D. Gabrić, "Application of Photodynamic Therapy in the Treatment of Osteonecrosis of the Jaw", Photodynamic Therapy - from Basic Science to Clinical Research, N. Inada, Ed. London : Delhi: IntechOpen, 2020, pp. 1-25. [Online] Available at: https://urn.nsk.hr/urn:nbn:hr:127:712112

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Metadata
Title (english)Application of Photodynamic Therapy in the Treatment of Osteonecrosis of the Jaw
AuthorMarko Vuletić
AuthorBožana Brzak Lončar
AuthorIgor Smojver
AuthorLuka Marković
AuthorMato Sušić
AuthorDragana Gabrić
EditorNatalia Inada
Author's institution(Zagreb University Hispital Center)
Author's institutionUniversity of Zagreb
School of Dental Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Dental Medicine
Oral Surgery
Abstract (english)
Osteonecrosis as term represents the death of bone tissue in the body and causes of necrosis can be different. Medication- related osteonecrosis of the jaws (MRONJ) is nowadays known as an inability of the alveolar bone to respond to a local trauma and it can result in severe local and systemic complications. In the etiology of medication- related osteonecrosis there are antiangiogenic and antiresorptive agents which have great effect on alveolar bone, producing an imbalance between resorption (osteoclastic activity) and deposition (osteoblastic activity). The exact mechanisms of development are not todays completely resolved. It is thought that it is a result from combination of medication interactions, microbiological contamination of the area and local tissue trauma. Typical signs and symptoms are painful mucosal lesions, swelling, exposed necrotic bone in the jaws, discomfort and dysesthesias. There is currently no gold standard or clearly defined treatment protocol for the disease itself. Process of treatment is demanding and main goal is to eliminate pain, control infection of soft and hard tissue and minimize progression of osteonecrosis. Besides the conventional surgical treatment, photodynamic therapy can be a viable supportive tool of initial and advanced stages of osteonecrosis and may contribute to improvements of patient′s quality of life.
Keywords (english)
Languageenglish
Publication typeProfessional paper - Chapter in Book
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Book titlePhotodynamic Therapy - from Basic Science to Clinical Research
Numberingpp. 1-25
ISBN978-1-83968-061-8
DOIhttps://doi.org/10.5772/intechopen.94257
URN:NBNurn:nbn:hr:127:712112
Publication2020
Type of resourceText
PublisherIntechOpen
Publishing placeLondon : Delhi
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) icon
Created on2023-10-20 09:16:49