Bioaktivni materijali za liječenje pulpe mladih trajnih zuba

master's thesis

• Title (english): Bioactive materials used in treatment of the pulp of immature permanent teeth
• Author: Lucija Šarić
• Mentor: Kristina Goršeta (mentor)
• Granter: University of Zagreb; School of Dental Medicine; Zagreb
• Defense date and country: 2023-09-29, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Dental Medicine; Children's and Preventive Dental Medicine

Abstract

Održavanje vitalnosti zubne pulpe je temeljni koncept modernog stomatološkog liječenja. Terapija vitalne pulpe uključuje postupke koji se izvode kako bi se održala zdrava pulpa zubi zahvaćenih karijesom ili traumom. Postupci koji se koriste uključuju prekrivanje pulpe (direktno ili indirektno) i vitalnu pulpotomiju (parcijalna ili totalna).
U tu svrhu razvijeni su mnogi sintetički materijali tijekom godina. Najviše se koriste kalcijev hidroksid (Ca(OH)2) i mineralni trioksidni agregat (MTA) koji se smatraju popularnim materijalima kako za prekrivanje pulpe tako i za postupke pulpotomije. Zbog napretka tehnologije i novih znanstvenih spoznaja proizvedeni su novi, bioaktivni materijali kao što su Biodentin, bioaktivno staklo, bioagregat, mješavina obogaćena kalcijem (CEM), kalcijev silikat (TheraCal LC) i biokeramički materijali (Endosequence).
Ipak, svi prethodno navedeni sintetički materijali induciraju reparativnu dentinogenezu do ograničene mjere, ali ne omogućavaju potpunu regeneraciju izgubljenog tkiva. Daljnja istraživanja usmjerena su na razvoj materijala i postupaka za inicijaciju regeneracije u pulpnom tkivu.

Abstract (english)

One of the fundamental concepts of modern dental treatment is to keep the dental pulp healthy and functional. Vital pulp therapy refers to a set of procedures that are performed to maintain the healthy pulp of teeth that have been affected by caries or trauma. These procedures include direct or indirect pulp capping, as well as partial or total vital pulpotomy.
Many synthetic materials have been developed for this purpose over the years. Calcium hydroxide (Ca(OH)2) and mineral trioxide aggregate (MTA) are most commonly used, and considered popular materials for both pulp capping and vital pulpotomy procedures. Due to technological progress and new scientific knowledge, new, bioactive materials such as Biodentin, bioactive glass, bioaggregate, calcium-enriched mixture (CEM), calcium silicate (TheraCal LC) and bioceramic materials (Endosequence) have been produced.
While synthetic materials do encourage some reparative dentinogenesis, they fall short of enabling complete regeneration of the lost tissue. As a result, current research is focused on developing treatments that can initiate the regeneration in pulp tissue.

• Keywords: CEM cement; dječja stomatologija; kalcijev hidroksid; MTA cement; prekrivanje pulpe; vitalnost pulpe
• Keywords (english): calcium hydroxide; CEM cement; MTA cement; pulp capping; pulp vitality; pediatric dentistry
• Language: croatian
• URN:NBN: urn:nbn:hr:127:365675
• Study programme: Title: dental medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica dentalne medicine (doktor/doktorica dentalne medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Access restricted to students and staff of home institution
• Created on: 2023-09-27 20:41:47