prikaz prve stranice dokumenta Inflammatory Biomarkers Affecting Survival Prognosis in Patients Receiving Veno-Venous ECMO for Severe COVID-19 Pneumonia
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Scientific paper - Original scientific paper
Inflammatory Biomarkers Affecting Survival Prognosis in Patients Receiving Veno-Venous ECMO for Severe COVID-19 Pneumonia
Diagnostics, 13 (2023), 13; 2203. https://doi.org/10.3390/diagnostics13132203
Drmić, Željka; Bandić, Ivan; Hleb, Sonja; Kukoč, Andrea; Sakan, Sanja; Sojčić, Nataša; Kristović, Darko; Mikecin, Verica; Presečki, Ivana; Oremuš, Zrinka Šafarić; Bradić, Nikola; Peršec, Jasminka; Šribar, Andrej

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Drmić, Ž., Bandić, I., Hleb, S., Kukoč, A., Sakan, S., Sojčić, N. ... Šribar, A. (2023). Inflammatory Biomarkers Affecting Survival Prognosis in Patients Receiving Veno-Venous ECMO for Severe COVID-19 Pneumonia. Diagnostics, 13. (13). doi: 10.3390/diagnostics13132203

Drmić, Željka, et al. "Inflammatory Biomarkers Affecting Survival Prognosis in Patients Receiving Veno-Venous ECMO for Severe COVID-19 Pneumonia." Diagnostics, vol. 13, no. 13, 2023. https://doi.org/10.3390/diagnostics13132203

Drmić, Željka, Ivan Bandić, Sonja Hleb, Andrea Kukoč, Sanja Sakan, Nataša Sojčić, Darko Kristović, et al. "Inflammatory Biomarkers Affecting Survival Prognosis in Patients Receiving Veno-Venous ECMO for Severe COVID-19 Pneumonia." Diagnostics 13, no. 13 (2023). https://doi.org/10.3390/diagnostics13132203

Drmić, Ž., et al. (2023) 'Inflammatory Biomarkers Affecting Survival Prognosis in Patients Receiving Veno-Venous ECMO for Severe COVID-19 Pneumonia', Diagnostics, 13(13). doi: 10.3390/diagnostics13132203

Drmić Ž, Bandić I, Hleb S, Kukoč A, Sakan S, Sojčić N, and sur.. Inflammatory Biomarkers Affecting Survival Prognosis in Patients Receiving Veno-Venous ECMO for Severe COVID-19 Pneumonia. Diagnostics [Internet]. 2023 June 28 [cited 2024 April 18];13(13). doi: 10.3390/diagnostics13132203

Ž. Drmić, et al., "Inflammatory Biomarkers Affecting Survival Prognosis in Patients Receiving Veno-Venous ECMO for Severe COVID-19 Pneumonia", Diagnostics, vol. 13, no. 13, June 2023. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:127:362542. [Accessed: 18 April 2024]

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Metadata
Title (english)Inflammatory Biomarkers Affecting Survival Prognosis in Patients Receiving Veno-Venous ECMO for Severe COVID-19 Pneumonia
AuthorŽeljka Drmić
AuthorIvan Bandić
AuthorSonja Hleb
AuthorAndrea Kukoč
AuthorSanja Sakan
AuthorNataša Sojčić
AuthorDarko Kristović
AuthorVerica Mikecin
AuthorIvana Presečki
AuthorZrinka Šafarić Oremuš
AuthorNikola Bradić
AuthorJasminka Peršec
AuthorAndrej Šribar
Author's institution(Dubrava University Hospital)
Author's institutionUniversity of Zagreb
School of Dental Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
Severe COVID-19 pneumonia in which mechanical ventilation is unable to achieve adequate gas exchange can be treated with veno-venous ECMO, eliminating the need for aggressive mechanical ventilation which might promote ventilator-induced lung injury and increase mortality. In this retrospective observational study, 18 critically ill COVID-19 patients who were treated using V-V ECMO during an 11-month period in a tertiary COVID-19 hospital were analyzed. Biomarkers of inflammation and clinical features were compared between survivors and non-survivors. Survival rates were compared between patients receiving ECMO and propensity matched mechanically ventilated controls. There were 7 survivors and 11 non-survivors. The survivors were significantly younger, with a higher proportion of females, higher serum procalcitonin at ICU admission, and before initiation of ECMO they had significantly lower Murray scores, PaCO2, WBC counts, serum ferritin levels, and higher glomerular filtration rates. No significant difference in mortality was found between patients treated with ECMO compared to patients treated using conventional lung protective ventilation. Hypercapnia, leukocytosis, reduced glomerular filtration rate, and increased serum ferritin levels prior to initiation of V-V ECMO in patients with severe COVID-19 pneumonia may be early warning signs of reduced chance of survival. Further multicentric studies are needed to confirm these findings.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleDiagnostics
Numberingvol. 13, no. 13, 2203
e-ISSN2075-4418
DOIhttps://doi.org/10.3390/diagnostics13132203
URN:NBNurn:nbn:hr:127:362542
Publication2023-06-28
Document URLhttps://www.mdpi.com/2075-4418/13/13/2203
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2023-08-21 08:03:48