Bioaktivni materijali za punjenje korijenskih kanala

master's thesis

• Title (english): Bioactive materials for root canal obturation
• Author: Fabijan Mišković
• Mentor: Ivana Miletić (mentor)
• Granter: University of Zagreb; School of Dental Medicine; Zagreb
• Defense date and country: 2023-06-21, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Dental Medicine

Abstract

Bioaktivni materijali sve se više koriste u endodonciji i u tu skupinu svrstavaju se oni materijali koji pobuđuju specifičan biološki odgovor i stvaraju svezu između tvrdog zubnog tkiva i samog materijala. Bioaktivni materijali proizvode se u različitim oblicima i različitog su sastava te se koriste za indirektno i direktno prekrivanje pulpe, ortogradno i retrogradno punjenje korijenskih kanala, zatvaranje perforacija, apeksifikaciju i apeksogenezu jer za razliku od tradicionalnih punila potiču diferencijaciju osteoblasta, što pridonosi bržem i boljem cijeljenju periapikalnog tkiva. Oni imaju sposobnost otpuštanja kalcijevih iona i stvaranja sloja kalcijevog hidroksida. U tu skupinu svrstavaju se hidraulički kalcij-silikatni cementi i materijali temeljeni na bioaktivnom staklu. Njihove su glavne prednosti što u reakciji s periapikalnim tkivom potiču njegovo cijeljenje, stvaranje mineralizacijske zone, netoksičnost, osteoindukcija, osteokondukcija, ubrzano cijeljenje tkiva, smanjuju vjerojatnost za nastanak mikropropuštanja te dobra sveza s tvrdim zubnim tkivom.

Abstract (english)

Bioactive materials are becoming more frequently used in endodontics. We refer to these materials as the ones capable of stimulating the specific biological response and creating a bond between the tooth's hard tissue and the material itself. Bioactive materials are manufactured in different forms and distinct composition and they are being used as materials for indirect and direct pulp capping procedure, orthograde and retrograde root canal obturation, closure of root perforations, apexification and apexogenesis on the grounds that these materials, in contrast to traditional endodontic sealers, prompt the differentiation of osteoblastic type cells which contribute to faster and better healing of the periapical tissue. These materials are capable of releasing calcium ions as well as forming a calcium hydroxide layer. Hydraulic calcium silicate cements and materials based on bioactive glass are included in this classification. The major advantages of these materials are that they induce tissue healing when in contact with the periapical tissue, formation of the mineralized zone, nontoxicity, osteoinduction, osteoconduction, accelerated tissue healing, decreasing the probability of microleakage effect as well as exhibiting a favourable bonding strength.

• Keywords: bioaktivni materijali; hidraulički kalcij-silikatni cementi; bioaktivno staklo
• Keywords (english): bioactive materials; hidraulic calcium silicate cements; bioactive glass; dental cements; root canal filling materials
• Language: croatian
• URN:NBN: urn:nbn:hr:127:771264
• Study programme: Title: dental medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica dentalne medicine (doktor/doktorica dentalne medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2023-06-16 11:32:35