Utjecaj kromosomskih poremećaja na procjenu dentalne dobi kod djece

master's thesis

• Title (english): Influence of chromosomal disorders on the assessment of dental age in children
• Author: Jana Belič
• Mentor: Ivana Savić Pavičin (mentor)
• Committee member: Ivana Savić Pavičin (predsjednik povjerenstva)
• Committee member: Maja Žagar (član povjerenstva)
• Committee member: Jelena Dumančić (član povjerenstva)
• Granter: University of Zagreb; School of Dental Medicine; (Department of Dental Anthropology); Zagreb
• Defense date and country: 2022-09-30, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Dental Medicine; Morphology of the Dental Tissue System

Abstract

Stupanj rasta i razvoja krune ili korijena, kao i vrijeme nicanja, bitni su elementi različitih
metoda za procjenu dentalne dobi kod živih osoba i kod skeletnih ostataka. Metode koje se
koriste dijele se na rendgenske (metoda po Demirjianu, Nolli, Moorreesu i Cameriereu) i atlasne
tehnike. Metode definiraju faze mineralizacije zuba uočene na rendgenskoj snimci i ocjenjuju
ih prema unaprijed određenim rezultatima. Određena sistemska stanja, kao što je Downov
sindrom, mogu uzrokovati odstupanja u maturaciji, pa tako može doći i do kašnjenja dentalnog
sazrijevanja. Kromosomski poremećaji svojim manifestacijama, kao što su zahtjevno
ponašanje, urođene mane, tjelesni invaliditeti i određeni kraniofacijalni nedostatci,
predstavljaju veliki izazov u svakodnevnoj stomatološkoj praksi, ali nova su istraživanja i
spoznaje od velike pomoći u kliničkoj praksi u različitim granama dentalne medicine, kao što
su orofacijalna genetika, ortodonocija, pedodoncija te forenzična stomatologija. Točni utjecaji
i mehanizmi reperkusije kromosomskih poremećaja na kraniofacijalni rast i razvoj na
molekularnoj su razini u velikoj mjeri još nerazjašnjeni i potrebna su daljnja istraživanja.
Trenutno je dostupan mali broj kontroliranih studija o utjecaju kromosomskih promjena na
dentalnu starost kod djece. Svrha rada je pregledom recentne literature prikazati kako
kromosomske promjene mogu utjecati na dentalni razvoj, a time i na procjenu dentalne dobi.

Abstract (english)

The stage of growth and development of the crown or the root, as well as the time of tooth
eruption, are essential elements of various methods employed for the assessment of the dental
age of living people and skeletal remains. The methods used are divided into X-ray (conceived
by Demirjian, Nolla, Moorrees and Cameriere) and Atlas techniques. The methods define the
stages of enamel development visible on an X-ray and estimate them according to the predefined results. Some conditions such as Down’s syndrome can cause deviations in maturation,
so that dental development might also be delayed. Manifestations of chromosomal disorders
(e.g. demanding behaviour, birth defects, physical disabilities, and certain craniofacial
disorders) pose a great challenge in everyday dental practice; however, new research and
insights are of great help in clinical practice in various branches of dental medicine, such as
orofacial genetics, orthodontics, pedodontics and forensic dentistry. The exact impact and
mechanisms of chromosomal disorders on craniofacial formation and development are for the
most part yet to be determined on the molecular level, and require further research. Currently,
there are few controlled studies on the impact of chromosomal change on the dental age of
children. The aim of this paper is to show by means of an overview of recently published
literature how changes can affect dental development and, consequently, dental age estimation.

• Keywords: denticija; kromosomski poremećaji
• Keywords (english): Dentition; Chromosome Disorders
• Language: croatian
• URN:NBN: urn:nbn:hr:127:850212
• Study programme: Title: dental medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica dentalne medicine (doktor/doktorica dentalne medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Access restricted to students and staff of home institution
• Created on: 2022-11-29 10:15:12