Alergije na materijale u dentalnoj medicini

master's thesis

• Title (english): Allergies to materials in dental medicine
• Author: Emma Toljan
• Mentor: Ketij Mehulić (mentor)
• Committee member: Ketij Mehulić (predsjednik povjerenstva)
• Committee member: Marko Jakovac (član povjerenstva)
• Committee member: Ana Andabak Rogulj (član povjerenstva)
• Granter: University of Zagreb; School of Dental Medicine; (Department of Fixed Prosthodontics); Zagreb
• Defense date and country: 2022-06-23, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Dental Medicine

Abstract

Alergija ili preosjetljivost je pretjerana reakcija organizma izazvana tvarima koji dovode do
oštećenja organizma. Reakcije preosjetljivosti u dentalnoj medicini su rijetke i najčešće se
pojavljuju kontaktne ili odgođene reakcije preosjetljivosti (tip IV) na različite metale, akrilate
ili ostale komponente dentalnih materijala u obliku lezija vidljivih na sluznici usne šupljine ili
koži, a mogu se manifestirati i u sustavnom obliku. Legure korištene u dentalnoj medicini
uslijed interakcija u usnoj šupljini podliježu elektrokemijskoj koroziji i tribokorozijskom
trošenju, a brojni gradivni i pomoćni materijali klasificirani su alergeni s velikom mogućnošću
izazivanja alergijskih reakcija. Korištenjem biokompatibilnih materijala čija je sigurnost
potvrđena laboratorijskim i kliničkim istraživanjima želi se smanjiti mogućnost nastanka
neželjenih reakcija. Najčešća metoda dokazivanja preosjetljivosti na neki materijal jest
epikutano ili patch testiranje, a ukoliko pacijent u svojoj anamnezi navodi alergiju na metale ili
neke druge materijale ili je preosjetljivost dokazana epikutanim testiranjem, navedeni
alergogeni materijal je potrebno zamijeniti nekim manje potentnim.

Abstract (english)

Allergy or hypersensitivity is an excessive reaction of the organism caused by substances that
cause damage to the organism. Hypersensitivity reactions in dental medicine are rare and most
often are contact or delayed hypersensitivity reactions (type IV) to various metals, acrylates or
other components of dental materials in the form of lesions visible on the oral mucosa or skin,
and may also manifest in systemic form. Alloys used in are subject to electrochemical corrosion
and tribocorrosion wear dentistry due to interactions in the oral cavity, and a number of
materials are classified as allergens with a high potential to cause allergic reactions. By using
biocompatible materials whose safety has been confirmed by laboratory and clinical research,
we want to reduce the possibility of adverse reactions. The most common method of proving
hypersensitivity to a material is epicutaneous or patch testing, and if the patient has a history of
allergy to metals or other materials, or hypersensitivity is proven by epicutaneous testing, the
allergenic material should be replaced with a less potent one.

• Keywords: alergijska reakcija ; preosjetljivost ; dentalni materijali ; alergeni ; biokompatibilnost ; oralna sluznica ; legure ; epikutano testiranje ; anamneza
• Keywords (english): allergic reaction ; hypersensitivity ; dental materials ; allergens ; biocompatibility ; oral mucosa ; alloys ; epicutaneous testing ; anamnesis
• Language: croatian
• URN:NBN: urn:nbn:hr:127:259731
• Study programme: Title: dental medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica dentalne medicine (doktor/doktorica dentalne medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2022-10-14 11:27:57