Utjecaj COVID-19 pandemije na potrošnju lijekova u dentalnoj medicini u Republici Hrvatskoj

master's thesis

• Title (english): The impact of the COVID-19 pandemic on the medication utilization in dentistry in the Republic of Croatia
• Author: Iva Plazonić
• Mentor: Ivana Šutej (mentor)
• Committee member: Ivana Šutej (predsjednik povjerenstva)
• Committee member: Kristina Peroš (član povjerenstva)
• Committee member: Krešimir Bašić (član povjerenstva)
• Granter: University of Zagreb; School of Dental Medicine; (Chair of Pharmacology); Zagreb
• Defense date and country: 2022-07-07, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Dental Medicine

Abstract

Novi koronavirus pojavio se u Kini krajem 2019. godine, a nazvan je SARS-CoV-2 (Severe
Acute Respiratory Syndrome Coronavirus-2). Radi se o novom soju koronavirusa koji prije nije
bio zabilježen kod ljudi. Bolest uzrokovana ovim virusom naziva se COVID-19.
COVID-19 pandemija imala je značajan utjecaj na pružanje stomatološke skrbi. Obustava rada
stomatoloških ordinacija onemogućila je kvalitetnu stomatološku obradu pacijenata. Utvrđeno
je značajno povećanje broja recepata izdanih od strane liječnika dentalne medicine. Uporaba
lijeka bez pravilne indikacije može dovesti do nepoželjnog razvoja mikrobne otpornosti i
smanjenja terapijske učinkovitosti zbog interakcije među lijekovima.
Svrha ovog rada bila je statistički prikazati potrošnju lijekova koje su propisali stomatolozi u
Republici Hrvatskoj u vremenskom periodu od 2019. do 2021. godine. Podatci korišteni u ovom
radu ustupljeni su od Hrvatskog zavoda za zdravstveno osiguranje (HZZO).
Najčešće propisivani lijekovi prema rezultatima ovog istraživanja bili su antibiotici.
Amoksicilin s klavulanskom kiselinom, antibakterijski lijek širokog spektra, imao je najveće
zabilježenu potrošnju. Lijekovi koji slijede antibiotike u učestalosti propisivanja jesu
nesteroidni protuupalni analgetici, najviše ibuprofen. Uočen je porast u propisivanju
antiseptičkih sredstava dok su antifungalni lijekovi pokazali padajući trend prema broju
propisanih recepata.
Posljedice koje su zahvatile hrvatski zdravstveni sustav za vrijeme pandemije, trebale bi
potaknuti cijelu stomatološku struku na promicanje odgovorne potrošnje svih vrsta lijekova.

Abstract (english)

A new coronavirus appeared in China at the end of 2019, which lead to its name SARS-CoV-2
(Severe Acute Respiratory Syndrome Coronavirus-2). It was a new strain of the coronavirus
that was not detected in humans in the past and the illness caused by the aforementioned virus
is referred to as COVID-19.
COVID-19 pandemic had a significant influence on dental care. The closure of dental practices
rendered high-quality medical treatment of dental patients impossible. There was a significant
increase in the number of prescriptions issued by practitioners of dental medicine. Using
medications without proper indications could lead to unwanted development of microbial
resistance and decrease in therapeutical effectiveness caused by interactions with other
medications.
The purpose of this paper is to present a statistical overview of the consumption of medications
issued by the dental practitioners in the Republic of Croatia during the period from 2019 until
2021. The data used in this paper was acquired with the help of the Croatian Health Insurance
Fund (HZZO – Hrvatski zavod za zdravstveno osiguranje).
According to the research, the most commonly issued prescriptions were those for antibiotics.
Amoxicillin with clavulanic acid, a broad-spectrum antibacterial medication, was the one that
was prescribed more often than any other medication. Medications that follow include
nonsteroidal anti-inflammatory drugs, out of which ibuprofen was the most prevalent. There
was also a noted increase in issuing antiseptics, while the antifungal medicines showed a decline
according to the number of issued prescriptions.
The consequences that had an effect on the entire healthcare system in the Republic of Croatia
during the pandemic should serve as an encouragement for everyone working in dental
medicine to advise responsible use of all types of medications.

• Keywords: stomatologija; COVID-19 pandemija; antibakterijska sredstva; terapija lijekovima
• Keywords (english): dentistry; COVID-19 pandemic; anti-bacterial agents; drug therapy
• Language: croatian
• URN:NBN: urn:nbn:hr:127:680440
• Study programme: Title: dental medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica dentalne medicine (doktor/doktorica dentalne medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2022-10-11 11:24:11