prikaz prve stranice dokumenta C-reactive protein, not cardiac troponin T, improves risk prediction in hypertensives with type A aortic dissection
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Scientific paper - Original scientific paper
C-reactive protein, not cardiac troponin T, improves risk prediction in hypertensives with type A aortic dissection
Blood Pressure, 24 (2015), 4; 212-216. https://doi.org/10.3109/08037051.2015.1025607
Vrsalovic, Mislav; Zeljkovic, Ivan; Presecki, Ana Vrsalovic; Pintaric, Hrvoje; Kruslin, Bozo

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Vrsalovic, M., Zeljkovic, I., Presecki, A. V., Pintaric, H. & Kruslin, B. (2015). C-reactive protein, not cardiac troponin T, improves risk prediction in hypertensives with type A aortic dissection. Blood Pressure, 24. (4), 212-216. doi: 10.3109/08037051.2015.1025607

Vrsalovic, Mislav, et al. "C-reactive protein, not cardiac troponin T, improves risk prediction in hypertensives with type A aortic dissection." Blood Pressure, vol. 24, no. 4, 2015, pp. 212-216. https://doi.org/10.3109/08037051.2015.1025607

Vrsalovic, Mislav, Ivan Zeljkovic, Ana Vrsalovic Presecki, Hrvoje Pintaric and Bozo Kruslin. "C-reactive protein, not cardiac troponin T, improves risk prediction in hypertensives with type A aortic dissection." Blood Pressure 24, no. 4 (2015): 212-216. https://doi.org/10.3109/08037051.2015.1025607

Vrsalovic, M., et al. (2015) 'C-reactive protein, not cardiac troponin T, improves risk prediction in hypertensives with type A aortic dissection', Blood Pressure, 24(4), pp. 212-216. doi: 10.3109/08037051.2015.1025607

Vrsalovic M, Zeljkovic I, Presecki AV, Pintaric H, Kruslin B. C-reactive protein, not cardiac troponin T, improves risk prediction in hypertensives with type A aortic dissection. Blood Pressure [Internet]. 2015 May 02 [cited 2025 January 02];24(4):212-216. doi: 10.3109/08037051.2015.1025607

M. Vrsalovic, I. Zeljkovic, A. V. Presecki, H. Pintaric and B. Kruslin, "C-reactive protein, not cardiac troponin T, improves risk prediction in hypertensives with type A aortic dissection", Blood Pressure, vol. 24, no. 4, pp. 212-216, May 2015. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:127:179944. [Accessed: 02 January 2025]

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Metadata
Title (english)C-reactive protein, not cardiac troponin T, improves risk prediction in hypertensives with type A aortic dissection
AuthorMislav Vrsalovic
AuthorIvan Zeljkovic
AuthorAna Vrsalovic Presecki
AuthorHrvoje Pintaric
AuthorBozo Kruslin
Author's institution(Sestre milosrdnice University Hospital Center)
Author's institutionUniversity of Zagreb
Faculty of Chemical Engineering and Technology
Author's institutionUniversity of Zagreb
School of Medicine
Author's institutionUniversity of Zagreb
School of Dental Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Dental Medicine
Abstract (english)
Background: The aim of the study was to evaluate prognostic role of inflammatory biomarkers, cardiac troponin T (cTnT) and D-dimer in type A acute aortic dissection (AAD) and to examine whether they might help in risk stratification beyond values of International Registry of Acute Aortic Dissection (IRAD) score. Methods: Baseline biomarkers were determined in 54 consecutive predominantly hypertensive patients with type A AAD and evaluated for in-hospital mortality. Results: After multivariable adjustment, the independent predictors of outcome were age (OR = 1.09; 95% CI 1.02-1.18), treatment strategy (OR = 0.11; 95% CI 0.02-0.06) and C-reactive protein (CRP) either as binary (OR = 7.06; 95% CI 1.34-37.36) or continuous variable (OR = 1.10; 95% CI 1.01-1.21). cTnT did not independently influence mortality. Receiver- operating characteristic (ROC) curve analysis showed significant link between CRP and outcome (area under the ROC curve, AUC = 0.79; p < 0.01). Values of CRP > 9.8 mg/l had 83% sensitivity and 80% specificity for predicting in-hospital mortality. Addition of CRP to IRAD score improved prediction of short-term outcome, AUC increased from 0.74 to 0.89 (p = 0.004). Conclusion: Admission CRP has independent prognostic value in type A AAD and the addition of CRP to IRAD score improved discriminative capacity of in-hospital mortality irrespective of symptom duration and treatment strategy.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleBlood Pressure
Numberingvol. 24, no. 4, pp. 212-216
p-ISSN0803-7051
e-ISSN1651-1999
DOIhttps://doi.org/10.3109/08037051.2015.1025607
URN:NBNurn:nbn:hr:127:179944
Publication2015-05-02
Document URLhttp://www.tandfonline.com/doi/full/10.3109/08037051.2015.1025607
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-10-30 09:36:46