Liječenje prekanceroza u usnoj šupljini

master's thesis

• Author: Nediljka Martinović
• Mentor: Mirko Ivkić (mentor)
• Granter: University of Zagreb; School of Dental Medicine; Zagreb
• Defense date and country: 2005, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Dental Medicine

Abstract

Prekanceroza je patološka promijena oralne sluznice koja se može transformirati u malignu leziju. U prekarcerozne lezije ubrajaju se eryhroplakia, leukoplakia, leukoplakia candidomycetica, lichen ruber i cheilitis actinica. Patohistološki gledano u oralnim prekancerozama dolazi do epitelne displazije. Velik broj podataka iz literature ukazuje, da oralne prekanceroze vrlo često prelaze u invazivni karcinom. Brojni etiološki faktori dovode do nastanka premalignih lezija, te postepeno i do njihove maligne alteracije. Zato prvo eliminiramo etiološke faktore, a onda pomoću konzervativne terapije liječimo ih ili zaliječimo. Konzervativno liječenje je moguće
različitim sredstvima koja inhibiraju imunološku reakciju, antimikrobnim lijekovima i analgeticima. Biopsija je kirurški postupak uzimanja uzoraka tkiva radi histopatološkog pregleda, a ekscizijska biopsija je i jedina terapija kod jačih displazija prekanceroza usne šupljine.

Abstract (english)

Precancerosis is a pathological alteration of oral mucosa which can be transformed into a malignant lesion. Precancerous lesions are erythroplakia, leucoplakia, leucoplakia candidomycetica, lichen ruber and cheilitis actinica. Pathohystologically, oral precancerous changes are epithelial dysplasia. Numerous data from literature indicates that oral precancerosis alternate to the form of invasive carcinoma. There are many etiologic factors which cause the initiation of premalignant lesions, and gradually to their malignant alteration. This is the reason why we try to eliminate the etiologic factors first, then treat the changes by means of conservative therapy. Conservative treatment includes different medications which inhibit the immunologic reaction, antimicrobial drugs and analgesics. Biopsy is a surgical procedure of sampling tissue for hystopathological examination. Excision biopsy is also the only therapy for severe dysplasia of oral cavity precancerosis.

• Keywords: tumori glave i vrata; usna šupljina
• Keywords (english): Head and neck neoplasms; Mouth
• Language: croatian
• URN:NBN: urn:nbn:hr:127:689884
• Study programme: Title: dental medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica dentalne medicine (doktor/doktorica dentalne medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Closed access
• Created on: 2024-05-16 11:24:25