Povezanost dijabetesa i hiposalivacije

master's thesis

• Title (english): Association between diabetes and hyposalivation
• Author: Ana Krolo
• Mentor: Vanja Vučićević-Boras (mentor)
• Committee member: Vanja Vučićević-Boras (predsjednik povjerenstva)
• Committee member: Nada Galić (član povjerenstva)
• Committee member: Anja Baraba (član povjerenstva)
• Granter: University of Zagreb; School of Dental Medicine; (Department of Oral Medicine); Zagreb
• Defense date and country: 2016-09-29, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Dental Medicine; Oral Medicine

Abstract

Šećerna bolest je metabolička bolest obilježena poremećajem metabolizma
ugljikohidrata, bjelančevina i masti gdje je primarno obilježje bolesti povišena razina
glukoze u krvi. Nastaje zbog poremećaja lučenja inzulina iz gušterače, promjena u
njegovom djelovanju ili oboje. Nekotrolirana hiperglikemija uzrokom je komplikacija
većeg broja organskih sustava uključujući oči, živce, bubrege i krvne žile. Najčešće oralne
manifestacije su halitoza, destrukcija alveolarne kosti, kserostomija, stomatopiroza,
inflamirana oralna sluznica sklona ozljedama, povećana sklonost infekcijama
(kandidijaza), povećan rizik za razvoj karijesa, parodontitis i povećana eksudacija iz
gingivnog sulkusa. U svrhu dokazivanja povezanosti dijabetesa i hiposalivacije pretražen
je Pubmed u zadnjih 10 godina s ključnim riječima: dijabetes, hiposalivacija i
kserostomija. Nađeno je 9 istraživačkih radova koji su proučavali međusobnu povezanost
dijabetesa, hiposalivacije i kserostomije. Različiti su autori došli do zaključka da postoji
hiposalivacija kod osoba oboljelih od dijabetesa te kako postoji značajna korelacija
između stupnja hiposalivacije i razine glukoze u slini. Dijabetes utječe na smanjenje pH
sline, a time i veću zastupljenost karijesa. Supstitucija sline može pomoći u smanjenju
vrijednosti plak indeksa.

Abstract (english)

Diabetes mellitus is a metabolic disease characterized by abnormal metabolism of
carbohydrates, proteins and fat where the primary characteristic of the disease are
elevated blood glucose levels. It occurs due to disturbances of insulin secretion from the
pancreas, a change in its activity or both. Uncontrolled hyperglycemia is a cause of
complications of a number of organ systems including eyes, nerves, kidneys and blood
vessels. The most common oral manifestations are halitosis, destruction of the alveolar
bone, xerostomia, Stomatopyrosis, inflamed oral mucosa prone to injuries, increased
susceptibility to infections (candidiasis), increased risk of developing caries,
periodontitis and increased exudation from gingival sulcus. For the purpose of proving
the association between diabetes and hyposalivation, Pubmed was searched in the last 10
years with the keywords: diabetes, hyposalivation and xerostomia. Nine research studies
were found that explored the interconnection of diabetes, hyposalivation and xerostomia.
Varoius authors concluded that hyposalivation exists in people with diabetes and that
there is a significant correlation between the degree of hyposalivation and glucose levels
in saliva. Diabetes tends to decrease the pH of saliva, and thus a increases risk for caries
development. Saliva substitutes can help reduce plaque index.

• Keywords: salivacija; šećerna bolest; komplikacije
• Keywords (english): salivation; diabetes complications
• Language: croatian
• URN:NBN: urn:nbn:hr:127:502899
• Study programme: Title: dental medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica dentalne medicine (doktor/doktorica dentalne medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2016-11-21 12:02:24