Suvremeni oralnokirurški pristup pacijenata zračenih u području glave i vrata

master's thesis

• Title (english): Modern oral surgical approach of patiens irradiated in the head and neck area
• Author: Ivan Bek
• Mentor: Tomislav Katanec (mentor)
• Committee member: Tomislav Katanec (predsjednik povjerenstva)
• Granter: University of Zagreb; School of Dental Medicine; Zagreb
• Defense date and country: 2023-07-06, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Dental Medicine

Abstract

Napretkom medicine i podizanjem svijesti ljudi o malignim bolestima, sve više se pacijentima otkrivaju karcinomi, kako u ranoj fazi tako i u uznapredovaloj. Uz kirurško liječenje, najčešće se primjenjuje terapija zračenjem ili kemoterapija. Radioterapija za sobom povlači nuspojave. Da bi se nuspojave svele na minimum, ključan zadatak stomatologa je informirati pacijenta, obaviti zahvate što bezbolnije i u pravo vrijeme te olakšati sam proces zračenja. Naglasak se stavlja na održavanju oralne higijene te na redovnim kontrolama. Kirurški zahvati bi se trebali obaviti prije početka terapije, za vrijeme terapije samo hitni zahvati, a nakon terapije treba dobro procijeniti rizik od nastanka neželjene nuspojave, osteoradionekroze. U današnje vrijeme sve se više istražuju novi pristupi onkološkim pacijentima kako bi se pacijentima poboljšala kvaliteta života. Najboljim potpornim metodama očuvanja kosti su se pokazali korištenje hiperbarične komore te korištenje plazme obogaćene faktorima rasta. Još uvijek je potrebno provoditi daljnja istraživanja i tragati za boljim rješenjima.

Abstract (english)

With the progress of medicine and raised awareness of malignant diseases, more patients are being diagnosed with cancer, both in the early and advanced stages. In addition to surgical treatment, radiotherapy and chemotherapy are most commonly used. However, radiotherapy entails certain side effects. In order to reduce its side effects to a minimum, it is crucial that dentists inform the patient, do their best to perform well-timed, painless procedures as well as facilitate the radiation process itself. Emphasis is placed on maintaining oral hygiene and regular check-ups. Surgical procedures should be performed before the start of therapy, whereas only emergency procedures should be carried out during therapy. After therapy, it is important to carefully assess the risk of an unwanted side effect, i.e. osteoradionecrosis occurring. Nowadays, there has been an increase in the research of new approaches to oncological patients in order to improve their quality of life. The use of hyperbaric chambers and plasma enriched with growth factors have proven to be the best supportive methods of bone preservation. However, it is still necessary to conduct further research and search for better solutions.

• Keywords: zračenje; osteoradionekroza; hiperbarična komora; kirurški zahvati; plazma obogaćena faktorima rasta; oralne novotvorine
• Keywords (english): radiation; osteoradionecrosis; hyperbaric chamber; surgical interventions; plasma enriched with growth factors; mouth neoplasms
• Language: croatian
• URN:NBN: urn:nbn:hr:127:709878
• Study programme: Title: dental medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica dentalne medicine (doktor/doktorica dentalne medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2023-07-03 11:37:19