Razvoj i značaj nuspojava u usnoj šupljini kao posljedica primjene sistemskog liječenja kolorektalnog karcinoma

master's thesis

• Title (english): DEVELOPMENT AND SIGNIFICANCE OF SIDE EFFECTS IN ORAL CAVITY AS A CONSEQUENCE OF SYSTEMIC TREATMENT OF COLORECTAL CARCINOMA
• Author: Tea Franković
• Mentor: Ana Fröbe (mentor)
• Committee member: Ana Fröbe
• Committee member: Ante Bolanča
• Committee member: Davor Vagić
• Granter: University of Zagreb; School of Dental Medicine; (Chair of Oncology and Nuclear Medicine); Zagreb
• Defense date and country: 2015-09-11, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Dental Medicine; Oral Medicine

Abstract

Kolorektalni karcinom jedna je od najčešćih malignih bolesti u današnjoj
populaciji.. Izbor liječenja ovisi o tipu, lokalizaciji i uznapredovalosti malignog
procesa. Kemoterapija, kao jedan od oblika liječenja, podrazumijeva sustavno
liječenje. Djeluje na tumorske stanice tako što sprečava njihov rast i razmnožavanje.
Ima i štetan učinak na normalne zdrave tkivne stanice, naročito na one koje se
ubrzano dijele, pa tako i na stanice usne šupljine. Najčešće nuspojave primjene
kemoterapije u usnoj šupljini su mukozitis, infekcije sluznice, suhoća usta,
poremećaj okusa, karijes i krvarenja. Stomatolog, primjenjujući odgovarajuće
liječenje, ima važnu ulogu u prevenciji i ublažavanju simptoma koji nastaju kao
posljedica primjene kemoterapije.

Abstract (english)

Colorectal carcinoma is one of the most frequent malignant diseases in the present-day population. The choice of treatment depends on the type, localization and progress of the malignant process. Chemotherapy, as one of the forms of treatment, implies systemic therapy. It affects tumour cells by preventing their growth and multiplication. It also has a harmful effect on normal healthy tissue cells, particularly on those that divide rapidly, including oral cavity cells. The most common side effects of chemotherapy that appear in the oral cavity are mucositis, infections of the mucous membrane, dryness of the mouth, taste disorders, caries and
bleeding. The stomatologist, using appropriate treatment, has an important role in the prevention and alleviation of symptoms that occur as a consequence of chemotherapy.

• Keywords: kolorektalne novotvorine; farmakoterapija; oralne bolesti
• Keywords (english): Colorectal Neoplasms; Drug Therapy; Mouth Diseases
• Language: croatian
• URN:NBN: urn:nbn:hr:127:268130
• Study programme: Title: Dental Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica dentalne medicine (doktor/doktorica dentalne medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2015-10-07 12:39:29