Promjene na koži lica inducirane UV-zračenjem

master's thesis

• Title (english): Ultraviolet light-induced lesions of the facial skin
• Author: Zrinka Bojčić
• Mentor: Marija Buljan (mentor)
• Committee member: Marija Buljan (predsjednik povjerenstva)
• Committee member: Liborija Lugović Mihić (član povjerenstva)
• Committee member: Marinka Mravak-Stipetić (član povjerenstva)
• Granter: University of Zagreb; School of Dental Medicine; (Chair of Dermatovenerology); Zagreb
• Defense date and country: 2016-09-16, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Dental Medicine

Abstract

Promjene inducirane UV zračenjem obuhvaćaju različite kliničke entitete. Zbog svoje biološke aktivnosti i sposobnosti da induciraju oštećenje DNK, UV-B zrake najvažniji su etiološki čimbenik u nastanku opeklina i karcinoma kože. Iako je UV-A zračenje glavna komponenta ultraljubičastog zračenja, manje je biološki aktivna od UV-B. UV-A zračenje ima posebno važnu ulogu u fotostarenju kože.
Klinička slika akutnih promjena induciranih UV zračenjem ovisi o količini energije apsorbirane u jednoj dozi te o fototipu kože. Akutne promjene inducirane UV zračenjem uključuju eritem, opekline, fotosenzitivne reakcije te fotodermatoze nepoznatog uzroka.
Kronične promjene nastaju kao posljedica dugotrajnog i kontinuiranog izlaganja UV zračenju. Prodiranjem UV zračenja, osobito UV-A zraka, dolazi do oštećenja elastičnih i kolagenih vlakana, što rezultira preuranjenim starenjem kože. Dugotrajna izloženost kože UV zračenju može dovesti do razvoja preinvazivnih, ali i invazivnih zloćudnih promjena kože. Kronične promjene kože inducirane UV zračenjem uključuju aktiničke keratoze, aktinički heilitis, bazocelularni i spinocelularni karcinom te melanom.

Abstract (english)

Ultraviolet light-induced skin lesions include varied clinical entities. Due to its damaging effect to DNA and their biological activity, UV-B radiation is the main cause of sunburn and skin cancer. Although UV-A radiation is the main component of ultraviolet radiation, it is less biologically active than UV-B. UV-A radiation has a substantial role in photoaging.
Clinical manifestations of acute UV light-induced skin lesions depend on the amount of energy absorbed in a single dose and skin phototype. Acute UV light-induced skin lesions include the following: erythema, sunburn, photosensitivity reactions and idiopathic photodermatoses.
Chronic UV-light induced skin lesions are the result of long-term and continuous exposure to UV radiation. The penetration of UV-radiation, especially UV-A rays, cause the damage of the elastic and collagen fibers, which results in the premature aging of the skin. Prolonged human exposure to solar UV radiation may result in pre-invasive and invasive skin lesions. Chronic UV light-induced skin lesions include the following: actinic keratoses, actinic cheilitis, and basal cell carcinoma, spinocellular carcinoma and melanoma.

• Keywords: kožne manifestacije; ultraljubičaste zrake; lice
• Keywords (english): skin manifestations; ultraviolet rays; face
• Language: croatian
• URN:NBN: urn:nbn:hr:127:091010
• Study programme: Title: dental medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica dentalne medicine (doktor/doktorica dentalne medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2016-11-02 11:32:35